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Article

Targeting BRAF in multiple myeloma.

Cancer discovery - 1 Aug 2013

O'Donnell Elizabeth, Raje Noopur S

Abstract excerpt

In multiple myeloma, it is believed that multiple mutations in different pathways deregulate the intrinsic biology of the plasma cell, resulting in a genetically complex heterogeneous disease. Mutations in the mitogen-activated protein kinase/extracellular signal-regulated kinase pathway have been identified and represent potential targets for therapy in this disease. BRAF, a serine/threonine kinase, has received...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23928771
DOI: 10.1158/2159-8290.CD-13-0297

Genes

BRAF

Provenance

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