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Article

The proprotein convertase subtilisin/kexin furinA regulates zebrafish host response against Mycobacterium marinum.

Infection and immunity - 1 Apr 2015

Ojanen Markus J T, Turpeinen Hannu, Cordova Zuzet M, Hammarén Milka M, Harjula Sanna-Kaisa E, Parikka Mataleena, Rämet Mika, Pesu Marko

Abstract excerpt

Tuberculosis is a chronic bacterial disease with a complex pathogenesis. An effective immunity against Mycobacterium tuberculosis requires both the innate and adaptive immune responses, including proper T helper (Th) type 1 cell function. FURIN is a proprotein convertase subtilisin/kexin (PCSK) enzyme, which is highly expressed in Th1 type cells. FURIN expression in T cells is essential for maintaining peripheral...

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Identifiers

PMID: 25624351
DOI: 10.1128/IAI.03135-14
PMCID: PMC4363408

Genes

FURIN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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