Article
Short QTc interval in males with klinefelter syndrome-influence of CAG repeat length, body composition, and testosterone replacement therapy.
Pacing and clinical electrophysiology : PACE - 1 Apr 2015
Jørgensen Inger Norlyk, Skakkebaek Anne, Andersen Niels Holmark, Pedersen Lisbeth Nørum, Hougaard David Michael, Bojesen Anders, Trolle Christian, Gravholt Claus Højbjerg
Abstract excerpt
BACKGROUND: Klinefelter syndrome (KS) is a sex chromosomal aneuploidy (47,XXY) affecting 1/660 males. Based on findings in Turner syndrome, we hypothesized that electrocardiogram (ECG) abnormalities would be present in males with KS. OBJECTIVE: To investigate ECGs in males with KS and compare with controls. METHODS: Case control study of 62 males with KS and 62 healthy males matched on age. The primary outcome...
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