Article
Membrane effects of N-terminal fragment of apolipoprotein A-I: a fluorescent probe study.
Journal of fluorescence - 1 Mar 2015
Trusova Valeriya, Gorbenko Galyna, Girych Mykhailo, Adachi Emi, Mizuguchi Chiharu, Sood Rohit, Kinnunen Paavo, Saito Hiroyuki
Abstract excerpt
The binding of monomeric and aggregated variants of 1-83 N-terminal fragment of apolipoprotein A-I with substitution mutations G26R, G26R/W@8, G26R/W@50 and G26R/W@72 to the model lipid membranes composed of phosphatidylcholine and its mixture with cholesterol has been investigated using fluorescent probes pyrene and Laurdan. Examination of pyrene spectral behavior did not reveal any marked influence of apoA-I...
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