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Article

The Epstein-Barr Virus Encoded BART miRNAs Potentiate Tumor Growth In Vivo

15 Jan 2015

Abstract excerpt

The human herpes virus Epstein-Barr virus (EBV) latently infects and drives the proliferation of B lymphocytes in vitro and is associated with several forms of lymphoma and carcinoma in vivo. The virus encodes ~30 miRNAs in the BART region, the function of most of which remains elusive. Here we have used a new mouse xenograft model of EBV driven carcinomagenesis to demonstrate that the BART miRNAs potentiate...

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PMID: 25590614
DOI: 10.1371/journal.ppat.1004561

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