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Article

Neonatal treatment of CINCA syndrome.

Pediatric rheumatology online journal - 1 Jan 2014

Paccaud Yan, Berthet Gerald, Von Scheven-Gête Annette, Vaudaux Bernard, Mivelaz Yvan, Hofer Michael, Roth-Kleiner Matthias

Abstract excerpt

UNLABELLED: Chronic Infantile Neurological Cutaneous Articular (CINCA) syndrome, also called Neonatal Onset Multisystem Inflammatory Disease (NOMID) is a chronic disease with early onset affecting mainly the central nervous system, bones and joints and may lead to permanent damage. We report two preterm infants with severe CINCA syndrome treated by anti-interleukin-1 in the neonatal period, although, so far, no...

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Source

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Identifiers

PMID: 25584041
DOI: 10.1186/1546-0096-12-52
PMCID: PMC4290099

Genes

NLRP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neonatal treatment of CINCA syndrome.PMID 25584041Read ↗

The clinical course of a child with CINCA/NOMID syndrome improved during and after treatment with thalidomide.Semantic proximity Read ↗

Chronic Infantile Neurological Cutaneous and Articular (CINCA) syndrome: a review.Semantic proximity Read ↗

[Significant effect of IL-1 receptor antagonist treatment in two patients who had CINCA syndrome with constant symptoms for 13 years].Semantic proximity Read ↗

Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition.Semantic proximity Read ↗

Current status of understanding the pathogenesis and management of patients with NOMID/CINCA.Semantic proximity Read ↗

Good response to IL-1beta blockade by anakinra in a 23-year-old CINCA/NOMID patient without mutations in the CIAS1 gene. Cytokine profiles and functional studies.Semantic proximity Read ↗

[Syndrome CINCA/NOMID].Semantic proximity Read ↗

Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes.Semantic proximity Read ↗

CIAS1 mutation in a patient with overlap between Muckle-Wells and chronic infantile neurological cutaneous and articular syndromes.Semantic proximity Read ↗

The pathogenesis of neonatal autoimmune and autoinflammatory diseases: a comprehensive review.Semantic proximity Read ↗

A severe case of chronic infantile neurologic, cutaneous, articular syndrome treated with biologic agents.Semantic proximity Read ↗

Detection of a novel mutation in NLRP3/CIAS1 gene in an Indian child with Neonatal-Onset Multisystem Inflammatory Disease (NOMID).Semantic proximity Read ↗

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