Article
Twin studies in multiple sclerosis: A meta-estimation of heritability and environmentality.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Oct 2015
Fagnani Corrado, Neale Michael C, Nisticò Lorenza, Stazi Maria A, Ricigliano Vito A, Buscarinu Maria C, Salvetti Marco, Ristori Giovanni
Abstract excerpt
BACKGROUND: Most twin studies of multiple sclerosis (MS) are inconclusive regarding the impact of genes and environment on disease susceptibility. In particular, high uncertainty exists about whether shared environmental factors are aetiologically relevant. OBJECTIVE: To disentangle, with a reasonable degree of confidence, the relative contributions of heritability and of shared and unique environmental...
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