Article
Association of matrix metalloproteinase-7 (-181A/G) promoter polymorphism in chronic pancreatitis.
The Indian journal of medical research - 1 Nov 2014
Manjari K Sri, Jyothy A, Kumar P Shravan, Prabhakar B, Nallari Pratibha, Venkateshwari A
Abstract excerpt
BACKGROUND & OBJECTIVES: Chronic pancreatitis is progressive and irreversible destruction of the pancreas. Matrix metalloproteinase-7 (MMP-7) is a secreted matrilysin, which contributes to angiogenesis and breakdown of basement membranes of pancreatic tissues. The present study was aimed to investigate the association of MMP-7 -181A/G (rs11568818) gene promoter polymorphism in patients with chronic pancreatitis....
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