Article
Linkage disequilibrium and haplotype block structure in a composite beef cattle breed.
BMC genomics - 1 Jan 2014
Mokry Fabiana Barichello, Buzanskas Marcos Eli, de Alvarenga Mudadu Maurício, do Amaral Grossi Daniela, Higa Roberto Hiroshi, Ventura Ricardo Vieira, de Lima Andressa Oliveira, Sargolzaei Mehdi, Conceição Meirelles Sarah Laguna, Schenkel Flávio Schramm, da Silva Marcos Vinicius Gualberto Barbosa, Méo Niciura Simone Cristina, de Alencar Maurício Mello, Munari Danísio, de Almeida Regitano Luciana Correia
Abstract excerpt
BACKGROUND: The development of linkage disequilibrium (LD) maps and the characterization of haplotype block structure at the population level are useful parameters for guiding genome wide association (GWA) studies, and for understanding the nature of non-linear association between phenotypes and genes. The elucidation of haplotype block structure can reduce the information of several single nucleotide...
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