Article
STARTVerso1: A randomized trial of faldaprevir plus pegylated interferon/ribavirin for chronic HCV genotype-1 infection.
Journal of hepatology - 1 Jun 2015
Ferenci Peter, Asselah Tarik, Foster Graham R, Zeuzem Stefan, Sarrazin Christoph, Moreno Christophe, Ouzan Denis, Maevskaya Marina, Calinas Filipe, Morano Luis E, Crespo Javier, Dufour Jean-François, Bourlière Marc, Agarwal Kosh, Forton Daniel, Schuchmann Marcus, Zehnter Elmar, Nishiguchi Shuhei, Omata Masao, Kukolj George, Datsenko Yakov, Garcia Miguel, Scherer Joseph, Quinson Anne-Marie, Stern Jerry O
Abstract excerpt
BACKGROUND & AIMS: The efficacy and tolerability of faldaprevir, a potent hepatitis C virus (HCV) NS3/4A protease inhibitor, plus peginterferon (PegIFN) and ribavirin (RBV) was assessed in a double-blind, placebo-controlled phase 3 study of treatment-naïve patients with HCV genotype-1 infection. METHODS: Patients were randomly assigned (1:2:2) to PegIFN/RBV plus: placebo (arm 1, n = 132) for 24 weeks; faldaprevir...
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