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Article

Fetal-onset IPEX: report of two families and review of literature.

Clinical immunology (Orlando, Fla.) - 1 Feb 2015

Xavier-da-Silva Mariana Moraes, Moreira-Filho Carlos A, Suzuki Edson, Patricio Francy, Coutinho Antonio, Carneiro-Sampaio Magda

Abstract excerpt

Early-life autoimmunity is an IPEX characteristic, however intrauterine forms had not yet been described. Here, two unrelated families with clear evidence of fetal-onset IPEX are reported. One had 5 miscarriages of males in two generations, and a newborn presenting type-1 diabetes mellitus immedi...

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Source

Identifiers

PMID: 25546394
DOI: 10.1016/j.clim.2014.12.007

Genes

FOXP3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25546394-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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