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Article

Decreased Notch Pathway Signaling in the Endometrium of Women With Endometriosis Impairs Decidualization

29 Dec 2014

Abstract excerpt

CONTEXT: Endometriosis is a common gynecological disease affecting one in 10 women of reproductive age and is a major cause of pelvic pain and impaired fertility. Endometrial stromal cells of women with endometriosis exhibit a reduced response to in vitro decidualization. NOTCH1 is critical for decidualization of both mouse and human uterine stromal cells. OBJECTIVE: This study aimed to determine whether...

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Identifiers

PMID: 25546156
DOI: 10.1210/jc.2014-3720

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Related research

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Research trail→

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Decreased Notch Pathway Signaling in the Endometrium of Women With Endometriosis Impairs DecidualizationPMID 25546156Read ↗

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ATOH8 Expression Is Regulated by BMP2 and Plays a Key Role in Human Endometrial Stromal Cell DecidualizationSemantic proximity Read ↗

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Endometrial stromal PRMT5 plays a crucial role in decidualization by regulating NF-κB signaling in endometriosisSemantic proximity Read ↗

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