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On the importance of targeting parasite stem cells in anti-echinococcosis drug development

1 Jan 2014

Abstract excerpt

The life-threatening diseases alveolar and cystic echinococcoses are caused by larvae of the tapeworms Echinococcus multilocularis and E. granulosus, respectively. In both cases, intermediate hosts, such as humans, are infected by oral uptake of oncosphere larvae, followed by asexual multiplication and almost unrestricted growth of the metacestode within host organs. Besides surgery, echinococcosis treatment...

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PMID: 25526547
DOI: 10.1051/parasite/2014070

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