Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA Profiling in Human Colon Cancer Cells during 5-Fluorouracil-Induced Autophagy

19 Dec 2014

Abstract excerpt

Autophagy modulation is now recognized as a potential therapeutic approach for cancer (including colorectal cancer), yet the molecular mechanisms regulating autophagy in response to cellular stress are still not well understood. MicroRNAs (miRNAs) have been found to play important roles in controlling many cellular functions, including growth, metabolism and stress response. The physiological importance of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Cancer-related molecular mechanisms research
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25526515
DOI: 10.1371/journal.pone.0114779

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA Profiling in Human Colon Cancer Cells during 5-Fluorouracil-Induced AutophagyPMID 25526515Read ↗

The effect of miRNA and autophagy on colorectal cancerSemantic proximity Read ↗

Inhibition of autophagy and tumor growth in colon cancer by miR-502Semantic proximity Read ↗

Colorectal cancer cells respond differentially to autophagy inhibition in vivoSemantic proximity Read ↗

mir-30d Regulates multiple genes in the autophagy pathway and impairs autophagy process in human cancer cellsSemantic proximity Read ↗

Over-expression of EGFR regulated by RARA contributes to 5-FU resistance in colon cancerSemantic proximity Read ↗

Colorectal cancer cells utilize autophagy to maintain mitochondrial metabolism for cell proliferation under nutrient stressSemantic proximity Read ↗

Negative Regulation of ULK1 by microRNA-106a in Autophagy Induced by a Triple Drug Combination in Colorectal Cancer Cells In VitroSemantic proximity Read ↗

MicroRNA expression profile of colon cancer stem-like cells in HT29 adenocarcinoma cell lineSemantic proximity Read ↗

Autophagy Is Activated in Colorectal Cancer Cells and Contributes to the Tolerance to Nutrient DeprivationSemantic proximity Read ↗

miR-338-3p confers 5-fluorouracil resistance in p53 mutant colon cancer cells by targeting the mammalian target of rapamycin.Semantic proximity Read ↗

Inhibition of Autophagy by 3-MA Enhances the Effect of 5-FU-Induced Apoptosis in Colon Cancer CellsSemantic proximity Read ↗

S-Adenosyl-l-Methionine Overcomes uL3-Mediated Drug Resistance in p53 Deleted Colon Cancer CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.