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Article

Over-expression of EGFR regulated by RARA contributes to 5-FU resistance in colon cancer

2 Jan 2020

Abstract excerpt

A promising new strategy for cancer therapy is to target the autophagic pathway. However, comprehensive characterization of autophagy genes and their clinical relevance in cancer is still lacking. Here, we systematically characterized alterations of autophagy genes in multiple cancer lines by analyzing data from The Cancer Genome Atlas and CellMiner database. Interactions between autophagy genes and clinically...

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PMID: 31896739
DOI: 10.18632/aging.102607

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