Article
Detection of genomic loci associated with environmental variables using generalized linear mixed models.
Genomics - 1 Feb 2015
Lobréaux Stéphane, Melodelima Christelle
Abstract excerpt
We tested the use of Generalized Linear Mixed Models to detect associations between genetic loci and environmental variables, taking into account the population structure of sampled individuals. We used a simulation approach to generate datasets under demographically and selectively explicit models. These datasets were used to analyze and optimize GLMM capacity to detect the association between markers and...
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