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Article

Molecular signatures that correlate with induction of lens regeneration in newts: lessons from proteomic analysis

1 Dec 2014

Abstract excerpt

BACKGROUND: Amphibians have the remarkable ability to regenerate missing body parts. After complete removal of the eye lens, the dorsal but not the ventral iris will transdifferentiate to regenerate an exact replica of the lost lens. We used reverse-phase nano-liquid chromatography followed by mass spectrometry to detect protein concentrations in dorsal and ventral iris 0, 4, and 8 days post-lentectomy. We...

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PMID: 25496664
DOI: 10.1186/s40246-014-0022-y

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