Article
Mycobacterial envelope lipids fingerprint from direct MALDI-TOF MS analysis of intact bacilli.
Tuberculosis (Edinburgh, Scotland) - 1 Jan 2015
Larrouy-Maumus Gérald, Puzo Germain
Abstract excerpt
Mycobacterium tuberculosis (Mtb) lipids including glycolipids and lipoglycans play a crucial role in the modulation of the host immune response by targeting the innate receptors C-type lectins, TLRs and the CD1 proteins of class 1. Glycolipids have been shown to be biomarkers of M. tuberculosis strains and also of opportunistic mycobacteria called non-tuberculous mycobacteria. Most of the structural and...
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