Article
Genetic analysis of Escherichia coli RadA: functional motifs and genetic interactions.
Molecular microbiology - 1 Mar 2015
Cooper Deani L, Boyle Daniel C, Lovett Susan T
Abstract excerpt
The RadA/Sms protein is a RecA-related protein found universally in eubacteria and plants, implicated in processing of recombination intermediates. Here we show that the putative Zn finger, Walker A motif, KNRXG motif and Lon protease homology domain of the Escherichia coli RadA protein are required for DNA damage survival. RadA is unlikely to possess protease activity as the putative active site serine is not...
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