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Article

Efficient and sustained IGF-1 expression in the adipose tissue-derived stem cells mediated via a lentiviral vector.

Journal of molecular histology - 1 Feb 2015

Chen Ting, Huang Dangsheng, Chen Guanghui, Yang Tingshu, Yi Jun, Tian Miao

Abstract excerpt

The adipose tissue-derived stem cells (ADSCs) represent a significant area of the cell therapy. Genetic modification of ADSCs may further improve their therapeutic potential. Here, we aimed to generate a lentiviral vector expressing insulin-like growth factor-I (IGF-1) and investigate the impact of IGF-1 transduction on the properties of cultured ADSCs. Isolated rat ADSCs were assessed by flow cytometric...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25467975
DOI: 10.1007/s10735-014-9599-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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