Article
Phenotype and physiological significance of the endocardial smooth muscle cells in human failing hearts.
Circulation. Heart failure - 1 Jan 2015
Okada Hideshi, Takemura Genzou, Kanamori Hiromitsu, Tsujimoto Akiko, Goto Kazuko, Kawamura Itta, Watanabe Takatomo, Morishita Kentaro, Miyazaki Nagisa, Tanaka Toshiki, Ushikoshi Hiroaki, Kawasaki Masanori, Miyazaki Tatsuhiko, Suzui Natsuko, Nishigaki Kazuhiko, Mikami Atsushi, Ogura Shinji, Minatoguchi Shinya
Abstract excerpt
BACKGROUND: Extravascular smooth muscle cells are often observed in the endocardium of human failing hearts. Here, we characterized the phenotype of those cells and investigated their physiological significance. METHODS AND RESULTS: We examined left ventricular biopsy specimens obtained from 44 patients with dilated cardiomyopathy and 6 nonfailing hearts. In Masson trichrome-stained histological preparations,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.