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Article

Characterization and genotyping of the DRB1 gene of the major histocompatibility complex (MHC) in the Marmota monax, animal model of hepatitis B.

Molecular immunology - 1 Feb 2015

Moreno-Cugnon Leire, Esparza-Baquer Aitor, Larruskain Amaia, García-Etxebarria Koldo, Menne Stephan, González-Aseguinolaza Gloria, Jugo Begoña M

Abstract excerpt

The major histocompatibility complex (MHC)-containing genes are among the most polymorphic in vertebrates. MHC genes code for proteins that are critical in the immune system response. In this study, the polymorphism of the second exon of the MHC class II DRB gene was characterized in the Eastern woodchuck (Marmota monax). Woodchucks chronically infected with the woodchuck hepatitis virus (WHV) represent the best...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25458311
DOI: 10.1016/j.molimm.2014.10.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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