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Article

A thiazepino[4,5-a]benzimidazole derivative hampers the RNA replication of Eurasian serotypes of foot-and-mouth disease virus.

Biochemical and biophysical research communications - 12 Dec 2014

Lefebvre David J, De Vleeschauwer Annebel R, Goris Nesya, Van Borm Steven, Chimirri Alba, Monforte Anna Maria, Valdazo-Gonzalez Begona, King Donald P, Neyts Johan, De Clercq Kris

Abstract excerpt

The stamping-out policy for the control of foot-and-mouth disease virus (FMDV) in countries that are free from FMD without vaccination has a dramatic socio-economic impact, huge animal welfare issues and may result in the loss of farm animal genetic resources. As an alternative to pre-emptive culling or emergency vaccination we further explore the possibility to use antiviral drugs in the event of an FMD...

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Identifiers

PMID: 25446115
DOI: 10.1016/j.bbrc.2014.11.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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