Article
Disparate detection outcomes for anti-HCV IgG and HCV RNA in dried blood spots.
Journal of virological methods - 1 Feb 2015
Tejada-Strop Alexandra, Drobeniuc Jan, Mixson-Hayden Tonya, Forbi Joseph C, Le Ngoc-Thao, Li Lixia, Mei Joanne, Terrault Norah, Kamili Saleem
Abstract excerpt
Dried blood spots (DBS) expedite the collection, storage and shipping of blood samples, thereby facilitating large-scale serologic studies. We evaluated the sensitivity of anti-HCV IgG testing and HCV-RNA quantitation using freshly prepared and stored DBS derived from HCV-infected patients. Protocols for elution were optimized using DBS prepared from plasma of 52 HCV-infected persons and 51 uninfected persons...
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