Article
Dried blood spot sampling for hepatitis B virus quantification, sequencing and mutation detection.
Scientific reports - 31 Jan 2022
Bezerra Cristianne Sousa, Portilho Moyra Machado, Barbosa Jakeline Ribeiro, de Azevedo Carolina Pimentel, Mendonça Ana Carolina da Fonseca, da Cruz José Napoleão Monte, Frota Cristiane Cunha, do Lago Bárbara Vieira, Villar Lívia Melo
Abstract excerpt
Hepatitis B virus (HBV) diagnosis is performed on serum samples, but the access to this diagnosis is difficult in low-income regions. The use of dried blood spot (DBS) samples does not require special structure for collection, storage or transport. This study evaluates the use of DBS for detection, quantification and sequencing of HBV DNA using in-house techniques. Two study groups were included: 92...
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