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Article

Characterization of <i>fosA5</i>, a new plasmid-mediated fosfomycin resistance gene in <i>Escherichia coli</i>

28 Nov 2014

Abstract excerpt

UNLABELLED: A clinical strain of extended-spectrum β-lactamase-producing Escherichia coli E265, with a fosfomycin MIC of 512 μg ml(-1), was isolated from an inpatient with hospital-acquired pneumonia. This strain was negative for known fos genes, had no mutation in the target enzyme by polymerase chain reaction amplification and had functional transport systems for fosfomycin uptake. Fosfomycin resistance could...

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PMID: 25441705
DOI: 10.1111/lam.12366

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