The role of microRNA-133b and its target gene FSCN1 in gastric cancer

Abstract excerpt

BACKGROUND: Increasing evidences have documented that microRNAs (miRNAs) act as oncogenes or tumor suppressors in gastric cancer (GC). In this study, we aimed to investigate the expression of miR-133b in a large number of GC samples and elucidate its role in GC carcinogenesis and the detailed mechanism. METHODS: We used Taqman probe stem-loop real-time PCR to accurately measure the levels of miR-133b in 100 pairs...

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