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Epstein-Barr virus and Burkitt lymphoma

21 Nov 2014

Abstract excerpt

In 1964, a new herpesvirus, Epstein-Barr virus (EBV), was discovered in cultured tumor cells derived from a Burkitt lymphoma (BL) biopsy taken from an African patient. This was a momentous event that reinvigorated research into viruses as a possible cause of human cancers. Subsequent studies demonstrated that EBV was a potent growth-transforming agent for primary B cells, and that all cases of BL carried...

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PMID: 25418195
DOI: 10.5732/cjc.014.10190

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