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Placental Inflammation in Preterm Premature Rupture of Membranes and Risk of Neurodevelopmental Disorders

24 Jun 2025

Abstract excerpt

Preterm premature rupture of membranes (pPROM) is a leading cause of preterm birth (PTB) and is increasingly recognized for its association with neurodevelopmental disorders (NDDs). The disruption of fetal membrane integrity introduces potential infection and inflammation into the intrauterine environment, triggering immune responses that may affect fetal development. Placental inflammation plays a pivotal role...

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PMID: 40643486
DOI: 10.3390/cells14130965

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