Article
Comparative genomics of mycobacteria: some answers, yet more new questions.
Cold Spring Harbor perspectives in medicine - 13 Nov 2014
Behr Marcel A
Abstract excerpt
Comparative genomic studies permit a genus-level perspective on the distinction between environmental mycobacteria and Mycobacterium tuberculosis, as well as a species-level assessment of genetic variability within M. tuberculosis. Both of these strata of evolutionary analysis serve to generate hypotheses regarding the genomic basis of M. tuberculosis virulence. In contrasting lessons from macroevolutionary study...
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