Article
Whole-genome phylogenomic heterogeneity of Neisseria gonorrhoeae isolates with decreased cephalosporin susceptibility collected in Canada between 1989 and 2013.
Journal of clinical microbiology - 1 Jan 2015
Demczuk Walter, Lynch Tarah, Martin Irene, Van Domselaar Gary, Graham Morag, Bharat Amrita, Allen Vanessa, Hoang Linda, Lefebvre Brigitte, Tyrrell Greg, Horsman Greg, Haldane David, Garceau Richard, Wylie John, Wong Tom, Mulvey Michael R
Abstract excerpt
A large-scale, whole-genome comparison of Canadian Neisseria gonorrhoeae isolates with high-level cephalosporin MICs was used to demonstrate a genomic epidemiology approach to investigate strain relatedness and dynamics. Although current typing methods have been very successful in tracing short-chain transmission of gonorrheal disease, investigating the temporal evolutionary relationships and geographical...
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