Article
Genomic epidemiology of Neisseria gonorrhoeae with reduced susceptibility to cefixime in the USA: a retrospective observational study.
The Lancet. Infectious diseases - 1 Mar 2014
Grad Yonatan H, Kirkcaldy Robert D, Trees David, Dordel Janina, Harris Simon R, Goldstein Edward, Weinstock Hillard, Parkhill Julian, Hanage William P, Bentley Stephen, Lipsitch Marc
Abstract excerpt
BACKGROUND: The emergence of Neisseria gonorrhoeae with decreased susceptibility to extended spectrum cephalosporins raises the prospect of untreatable gonorrhoea. In the absence of new treatments, efforts to slow the increasing incidence of resistant gonococcus require insight into the factors that contribute to its emergence and spread. We assessed the relatedness between isolates in the USA and reconstructed...
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