Article
Influence of virulence genotype and resistance profile in the mortality of Pseudomonas aeruginosa bloodstream infections.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Feb 2015
Peña Carmen, Cabot Gabriel, Gómez-Zorrilla Silvia, Zamorano Laura, Ocampo-Sosa Alain, Murillas Javier, Almirante Benito, Pomar Virginia, Aguilar Manuela, Granados Ana, Calbo Esther, Rodríguez-Baño Jesús, Rodríguez-López Fernando, Tubau Fe, Martínez-Martínez Luis, Oliver Antonio
Abstract excerpt
BACKGROUND: The type III secretion system (TTSS) is a major virulence determinant of Pseudomonas aeruginosa. The objective of this study was to determine whether the TTSS genotype is a useful prognostic marker of P. aeruginosa bacteremia mortality. We also studied the potential association between TTSS genotypes and multidrug-resistant (MDR) profiles, and how this interaction impacts the outcome of bloodstream...
Topics
- Adult
- Aged
- Aged, 80 and over
- Anti-Bacterial Agents
- Bacteremia
- Bacterial Proteins
- Bacterial Secretion Systems
- Drug Resistance, Bacterial