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Article

Quantitation of CYP24A1 enzymatic activity with a simple two-hybrid system.

The Journal of clinical endocrinology and metabolism - 1 Feb 2015

Mugg Amy, Legeza Balazs, Tee Meng Kian, Damm Izabella, Long Roger K, Miller Walter L

Abstract excerpt

CONTEXT: Mutations of the CYP24A1 gene encoding the 24-hydroxylase (24OHase) that inactivates metabolites of vitamin D can cause hypercalcemia in infants and adults; in vitro assays of 24OHase activity have been difficult. OBJECTIVE: We sought an alternative assay to characterize a CYP24A1 mutati...

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Identifiers

PMID: 25375986
DOI: 10.1210/jc.2014-3365
PMCID: PMC4318902

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25375986-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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