Article
PRKCH 1425G/A Polymorphism Predicts Recurrence of Ischemic Stroke in a Chinese Population.
Molecular neurobiology - 1 Dec 2015
Zhang Zhizhong, Xu Gelin, Zhu Wusheng, Cao Liping, Yan Bernard, Liu Xinfeng
Abstract excerpt
A recent genome-wide association study (GWAS) identified a nonsynonymous SNP (1425G/A) in PRKCH which was associated with increased risk of ischemic stroke. The purpose of this study was to examine whether this functional polymorphism is associated with stroke onset and prognosis in a Chinese population. We genotyped PRKCH 1425G/A using Improved Multiple Ligase Detection Reaction in 919 patients with ischemic...
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