Article
Impact of the 1425G/A polymorphism of PRKCH on the recurrence of ischemic stroke: Fukuoka Stroke Registry.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Jul 2014
Matsuo Ryu, Ago Tetsuro, Hata Jun, Kuroda Junya, Wakisaka Yoshinobu, Sugimori Hiroshi, Kitazono Takanari, Kamouchi Masahiro
Abstract excerpt
BACKGROUND: Epidemiologic studies have elucidated that the 1425G/A single-nucleotide polymorphism (rs2230500 single-nucleotide polymorphism) in exon 9 of the protein kinase C eta (PRKCH) gene is an independent risk factor for ischemic stroke: stroke incidence is significantly higher in the subjects with AA than those with AG or GG genotype. However, its impact on stroke recurrence remains unknown. The aim of the...
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