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Article

Presence of C1-inhibitor polymers in a subset of patients suffering from hereditary angioedema.

PloS one - 1 Jan 2014

Madsen Daniel Elenius, Hansen Søren, Gram Jørgen, Bygum Anette, Drouet Christian, Sidelmann Johannes Jakobsen

Abstract excerpt

Hereditary angioedema (HAE) is a potentially life-threatening disease caused by mutations in the gene encoding the serine protease inhibitor (serpin) C1 inhibitor (C1-inh). The mutations cause decreased functional plasma levels of C1-inh, which triggers unpredictable recurrent edema attacks. Subjects suffering from HAE have been classified in type I patients with decreased functional and antigenic levels of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25369003
DOI: 10.1371/journal.pone.0112051
PMCID: PMC4219832

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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