Article
FTO rs9939609 polymorphism is associated with metabolic disturbances and response to HCV therapy in HIV/HCV-coinfected patients.
BMC medicine - 3 Nov 2014
Pineda-Tenor Daniel, Berenguer Juan, Jiménez-Sousa María A, García-Alvarez Mónica, Aldámiz-Echevarria Teresa, Carrero Ana, Vázquez-Morón Sonia, García-Broncano Pilar, Diez Cristina, Tejerina Francisco, Guzmán-Fulgencio María, Resino Salvador
Abstract excerpt
BACKGROUND: The Fat Mass and Obesity-Associated Protein (FTO) gene rs9939609 single nucleotide polymorphism (SNP) has been associated with obesity, metabolic syndrome, insulin resistance (IR), and type 2 diabetes mellitus in the general population. The aim of our study was to examine for the first time the association of the rs9939609 polymorphism with metabolic disturbances, liver disease and virologic response...
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