Article
Medical reversal of chronic sinusitis in a cystic fibrosis patient with ivacaftor.
International forum of allergy & rhinology - 1 Feb 2015
Chang Eugene H, Tang Xiao Xiao, Shah Viral S, Launspach Janice L, Ernst Sarah E, Hilkin Brieanna, Karp Philip H, Abou Alaiwa Mahmoud H, Graham Scott M, Hornick Douglas B, Welsh Michael J, Stoltz David A, Zabner Joseph
Abstract excerpt
BACKGROUND: Chronic sinusitis is universal in cystic fibrosis (CF) and our current treatments are ineffective in reversing sinus disease. The objective of this work was to determine if increasing CF transmembrane conductance regulator (CFTR) activity by ivacaftor could treat CF sinus disease and assess its effect on primary sinus epithelial cultures. METHODS: Case report of 1 patient with long-standing chronic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.