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Article

Apolipoprotein E gene polymorphisms are associated with primary hyperuricemia in a Chinese population.

PloS one - 1 Jan 2014

Wu Jie, Qiu Ling, Guo Xiu-zhi, Xu Tao, Cheng Xin-qi, Zhang Lin, Li Peng-chang, Di Qian, Wang Qing, Ni Lan, Zhu Guang-jin

Abstract excerpt

OBJECTIVE: Primary hyperuricemia, an excess of uric acid in the blood, is a major public health problem. In addition to the morbidity that is attributable to gout, hyperuricemia is also associated with metabolic syndrome, hypertension, and cardiovascular disease. This study aims to assess the genetic associations between Apolipoprotein E (APOE) polymorphisms and hyperuricemia in a Chinese population. METHODS: A...

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Source

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Identifiers

PMID: 25356596
DOI: 10.1371/journal.pone.0110864
PMCID: PMC4214707

Genes

APOE
DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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