Article
Evidence for a genetic basis of urogenital carcinoma in the wild California sea lion.
Proceedings. Biological sciences - 7 Dec 2014
Browning Helen M, Acevedo-Whitehouse Karina, Gulland Frances M D, Hall Ailsa J, Finlayson Jeanie, Dagleish Mark P, Billington Karen J, Colegrove Kathleen, Hammond John A
Abstract excerpt
Although neoplasia is a major cause of mortality in humans and domestic animals, it has rarely been described in wildlife species. One of the few examples is a highly prevalent urogenital carcinoma in California sea lions (CSLs). Although the aetiology of this carcinoma is clearly multifactorial, inbreeding depression, as estimated using levels of microsatellite multilocus heterozygosity, is identified as...
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