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An immunogenetic basis for the high prevalence of urogenital cancer in a free-ranging population of California sea lions (Zalophus californianus).

Immunogenetics - 1 Feb 2005

Bowen Lizabeth, Aldridge Brian M, Delong Robert, Melin Sharon, Buckles Elizabeth L, Gulland Frances, Lowenstine Linda J, Stott Jeffrey L, Johnson Michael L

Abstract excerpt

In response to an unprecedented prevalence of cancer recently identified in free-ranging populations of California sea lions [(CSL) (Zalophus californianus], we examined the role of the immunologically important major histocompatibility (MHC) genes in this disease epidemic. Associations between MHC genes and cancer have been well established in humans, but have never before been investigated in wildlife. Using a...

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PMID: 15650877
DOI: 10.1007/s00251-004-0757-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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