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Article

MicroRNA expression profiles associated with acquired gefitinib-resistance in human lung adenocarcinoma cells

23 Oct 2014

Abstract excerpt

The aim of the present study was to establish, characterize and elucidate the potential mechanisms of acquired gefitinb resistance, using the A549 human lung cancer cell line. A gefitinib-resistant A549 sub-clone was established by exposure to escalating gefitinib concentrations over a period of 16-24 months. Half maximal inhibitory concentration (IC50) values were quantified using a real time cytotoxicity assay....

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Share to Cholangiocarcinoma and Gallbladder Cancer Studies
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Identifiers

PMID: 25339453
DOI: 10.3892/mmr.2014.2757

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