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Article

Identification of PAQR3 as a new candidate tumor suppressor in hepatocellular carcinoma

6 Oct 2014

Abstract excerpt

Progestin and adipoQ receptor family member III (PAQR3) is a regulator that negatively modulates the Ras/Raf/MEK/ERK signaling cascade and the GPCR Gβγ subunit signaling pathway. The role of PAQR3 in hepatocellular carcinoma (HCC) has not been elucidated. The present study investigated the expression of PAQR3 and its prognostic value in primary HCC patients. Furthermore, the functional aspects of PAQR3 were also...

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PMID: 25310770
DOI: 10.3892/or.2014.3532

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