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Article

Morphogenesis and molecular considerations on congenital cardiac septal defects

13 Oct 2014

Abstract excerpt

The primary unseptated heart tube undergoes extensive remodeling including septation at the atrial, atrioventricular, ventricular, and ventriculo-arterial level. Alignment and fusion of the septal components is required to ensure full septation of the heart. Deficiencies lead to septal defects at various levels. Addition of myocardium and mesenchymal tissues from the second heart field (SHF) to the primary heart...

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PMID: 25307363
DOI: 10.3109/07853890.2014.959557

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