Article
Copy number variants in short children born small for gestational age.
Hormone research in paediatrics - 1 Jan 2014
Wit Jan M, van Duyvenvoorde Hermine A, van Klinken Jan B, Caliebe Janina, Bosch Cathy A J, Lui Julian C, Gijsbers Antoinet C J, Bakker Egbert, Breuning Martijn H, Oostdijk Wilma, Losekoot Monique, Baron Jeffrey, Binder Gerhard, Ranke Michael B, Ruivenkamp Claudia A L
Abstract excerpt
BACKGROUND/AIMS: In addition to genome-wide association studies (GWAS), height-associated genes may be uncovered by studying individuals with extreme short or tall stature. METHODS: Genome-wide analysis for copy number variants (CNVs), using single nucleotide polymorphism (SNP) arrays, was performed in 49 index cases born small for gestational age with persistent short stature. Segregation analysis was performed,...
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