Article
Serotonin transporter polymorphism modifies the association between depressive symptoms and sleep onset latency complaint in elderly people: results from the 'InveCe.Ab' study.
Journal of sleep research - 1 Apr 2015
Polito Letizia, Davin Annalisa, Vaccaro Roberta, Abbondanza Simona, Govoni Stefano, Racchi Marco, Guaita Antonio
Abstract excerpt
Previous studies have documented the involvement of the central nervous system serotonin in promoting wakefulness. There are few and conflicting results over whether there is an actual association between bearing the short allele of serotonin transporter promoter polymorphism (5-HTTLPR) and worse sleep quality. This study examined whether sleep onset latency complaint is associated with the 5-HTTLPR triallelic...
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