Replicability and robustness of genome-wide-association studies for behavioral traits.

doi:10.1177/0956797614545132

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Replicability and robustness of genome-wide-association studies for behavioral traits.

Psychological science - 1 Nov 2014

Rietveld Cornelius A, Conley Dalton, Eriksson Nicholas, Esko Tõnu, Medland Sarah E, Vinkhuyzen Anna A E, Yang Jian, Boardman Jason D, Chabris Christopher F, Dawes Christopher T, Domingue Benjamin W, Hinds David A, Johannesson Magnus, Kiefer Amy K, Laibson David, Magnusson Patrik K E, Mountain Joanna L, Oskarsson Sven, Rostapshova Olga, Teumer Alexander, Tung Joyce Y, Visscher Peter M, Benjamin Daniel J, Cesarini David, Koellinger Philipp D

Abstract excerpt

A recent genome-wide-association study of educational attainment identified three single-nucleotide polymorphisms (SNPs) whose associations, despite their small effect sizes (each R (2) ≈ 0.02%), reached genome-wide significance (p < 5 × 10(-8)) in a large discovery sample and were replicated in an independent sample (p < .05). The study also reported associations between educational attainment and indices of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Educational Status

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Massachusetts

Share to Polymorphism, Single Nucleotide

Share to Principal Component Analysis

Share to Queensland

Share to Registries

Share to Reproducibility of Results

Source

Open in PubMed Open full text

Identifiers

PMID: 25287667
DOI: 10.1177/0956797614545132
PMCID: PMC4375246

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Replicability and robustness of genome-wide-association studies for behavioral traits.PMID 25287667Read ↗

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment.Semantic proximity Read ↗

Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.Semantic proximity Read ↗

Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals.Semantic proximity Read ↗

Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction.Semantic proximity Read ↗

Results of a "GWAS plus:" general cognitive ability is substantially heritable and massively polygenic.Semantic proximity Read ↗

A three-stage genome-wide association study of general cognitive ability: hunting the small effects.Semantic proximity Read ↗

Validating Online Measures of Cognitive Ability in Genes for Good, a Genetic Study of Health and Behavior.Semantic proximity Read ↗

Genome-wide association studies establish that human intelligence is highly heritable and polygenic.Semantic proximity Read ↗

Genetic sensitivity analysis: Adjusting for genetic confounding in epidemiological associations.Semantic proximity Read ↗

Predicting educational achievement from DNA.Semantic proximity Read ↗

Why it is hard to find genes associated with social science traits: theoretical and empirical considerations.Semantic proximity Read ↗

Genome-wide association study identifies 74 loci associated with educational attainment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.