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Increasing the discrimination power of ancestry- and identity-informative SNP loci within the ForenSeq™ DNA Signature Prep Kit.

Forensic science international. Genetics - 1 Sept 2018

King Jonathan L, Churchill Jennifer D, Novroski Nicole M M, Zeng Xiangpei, Warshauer David H, Seah Lay-Hong, Budowle Bruce

Abstract excerpt

The use of single nucleotide polymorphisms (SNPs) in forensic genetics has been limited to challenged samples with low template and/or degraded DNA. The recent introduction of massively parallel sequencing (MPS) technologies has expanded the potential applications of these markers and increased the discrimination power of well-established loci by considering variation in the flanking regions of target loci. The...

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PMID: 29935396
DOI: 10.1016/j.fsigen.2018.06.005

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