Article
Mycobacterium genotypes in pulmonary tuberculosis infections and their detection by trained African giant pouched rats.
Current microbiology - 1 Feb 2015
Mgode Georgies F, Cohen-Bacrie Stéphan, Bedotto Marielle, Weetjens Bart J, Cox Christophe, Jubitana Maureen, Kuipers Dian, Machang'u Robert S, Kazwala Rudovick, Mfinanga Sayoki G, Kaufmann Stefan H E, Drancourt Michel
Abstract excerpt
Tuberculosis (TB) diagnosis in low-income countries is mainly done by microscopy. Hence, little is known about the diversity of Mycobacterium spp. in TB infections. Different genotypes or lineages of Mycobacterium tuberculosis vary in virulence and induce different inflammatory and immune responses. Trained Cricetomys rats show a potential for rapid diagnosis of TB. They detect over 28 % of smear-negative,...
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